All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 1:25 PM ET.
| Rank | Player | Match |
| 1 | Cooper Kupp | LAR vs Sea |
| 2 | Jonathan Taylor | Ind @ Ari |
| 3 | Davante Adams | GB vs Cle |
| 4 | Alvin Kamara | NO vs Mia |
| 5 | Alexander Mattison | Min vs LAR |
| 6 | Justin Jefferson | Min vs LAR |
| 7 | James Robinson | Jax @ NYJ |
| 8 | Najee Harris | Pit @ KC |
| 9 | Tyreek Hill (GTD) | KC vs Pit |
| 10 | Nick Chubb | Cle @ GB |
| 11 | Cordarrelle Patterson | Atl vs Det |
| 12 | Josh Jacobs | LV vs Den |
| 13 | Aaron Jones | GB vs Cle |
| 14 | Joe Mixon | Cin vs Bal |
| 15 | Keenan Allen | LAC @ Hou |
| 16 | D'Andre Swift (GTD) | Det @ Atl |
| 17 | David Montgomery | Chi @ Sea |
| 18 | Stefon Diggs | Buf @ NE |
| 19 | Antonio Gibson (GTD) | Wsh @ Phi |
| 20 | Ezekiel Elliott | Dal vs Wsh |
| 21 | Saquon Barkley | NYG @ Phi |
| 22 | Diontae Johnson | Pit @ KC |
| 23 | Travis Kelce (GTD) | KC vs Pit |
| 24 | Ja'Marr Chase | Cin vs Bal |
| 25 | Antonio Brown | TB @ Car |
| 26 | CeeDee Lamb | Dal vs Wsh |
| 27 | James Conner (GTD) | Ari vs Ind |
| 28 | Tyler Lockett | Sea vs Chi |
| 29 | Miles Sanders | Phi vs Wsh |
| 30 | Ronald Jones | TB @ Car |
| 31 | Michael Pittman Jr. | Ind @ Ari |
| 32 | Tee Higgins | Cin vs Bal |
| 33 | Hunter Renfrow | LV vs Den |
| 34 | Rob Gronkowski | TB @ Car |
| 35 | Michael Carter | NYJ vs Jax |
| Rank | Player | Match |
| 36 | Mark Andrews | Bal @ Cin |
| 37 | D.K. Metcalf | Sea vs Chi |
| 38 | Russell Gage | Atl vs Det |
| 39 | Austin Ekeler (GTD) | LAC @ Hou |
| 40 | Clyde Edwards-Helaire | KC vs Pit |
| 41 | Javonte Williams | Den @ LV |
| 42 | Mike Williams | LAC @ Hou |
| 43 | Terry McLaurin | Wsh @ Phi |
| 44 | Marquise Brown | Bal @ Cin |
| 45 | Melvin Gordon | Den @ LV |
| 46 | D.J. Moore (GTD) | Car vs TB |
| 47 | Jaylen Waddle | Mia @ NO |
| 48 | Amari Cooper | Dal vs Wsh |
| 49 | Kyle Pitts | Atl vs Det |
| 50 | Christian Kirk | Ari vs Ind |
| 51 | Brandin Cooks (GTD) | Hou vs LAC |
| 52 | Devonta Freeman | Bal @ Cin |
| 53 | Darrell Henderson | LAR vs Sea |
| 54 | A.J. Dillon | GB vs Cle |
| 55 | Amon-Ra St. Brown | Det @ Atl |
| 56 | Jarvis Landry | Cle @ GB |
| 57 | DeVonta Smith | Phi vs Wsh |
| 58 | Tony Pollard | Dal vs Wsh |
| 59 | Dallas Goedert | Phi vs Wsh |
| 60 | Devin Singletary | Buf @ NE |
| 61 | Van Jefferson | LAR vs Sea |
| 62 | Odell Beckham | LAR vs Sea |
| 63 | Michael Gallup | Dal vs Wsh |
| 64 | Sony Michel | LAR vs Sea |
| 65 | Chase Claypool | Pit @ KC |
| 66 | Jakobi Meyers | NE vs Buf |
| 67 | Adam Thielen (GTD) | Min vs LAR |
| 68 | DeVante Parker | Mia @ NO |
| 69 | Rashaad Penny | Sea vs Chi |
| 70 | Justin Jackson | LAC @ Hou |
