All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 9:59 AM ET.
| Rank | Player | Match |
| 1 | Derrick Henry | Ten vs KC |
| 2 | Alvin Kamara | NO @ Sea |
| 3 | Darrell Henderson | LAR vs Det |
| 4 | Aaron Jones | GB vs Wsh |
| 5 | Jonathan Taylor | Ind @ SF |
| 6 | Leonard Fournette | TB vs Chi |
| 7 | Chuba Hubbard | Car @ NYG |
| 8 | D'Andre Swift | Det @ LAR |
| 9 | Joe Mixon | Cin @ Bal |
| 10 | Josh Jacobs | LV vs Phi |
| 11 | Darrel Williams | KC @ Ten |
| 12 | Devontae Booker | NYG vs Car |
| 13 | Miles Sanders | Phi @ LV |
| 14 | Antonio Gibson (GTD) | Wsh @ GB |
| 15 | Mike Davis | Atl @ Mia |
| 16 | Chase Edmonds | Ari vs Hou |
| 17 | Eli Mitchell | SF vs Ind |
| 18 | Damien Harris | NE vs NYJ |
| 19 | James Conner | Ari vs Hou |
| 20 | Myles Gaskin | Mia vs Atl |
| Rank | Player | Match |
| 21 | Michael Carter | NYJ @ NE |
| 22 | Alex Collins (GTD) | Sea vs NO |
| 23 | Khalil Herbert | Chi @ TB |
| 24 | A.J. Dillon | GB vs Wsh |
| 25 | J.D. McKissic | Wsh @ GB |
| 26 | Damien Williams | Chi @ TB |
| 27 | Mark Ingram | Hou @ Ari |
| 28 | Devonta Freeman | Bal vs Cin |
| 29 | Jamaal Williams | Det @ LAR |
| 30 | Sony Michel | LAR vs Det |
| 31 | Kenneth Gainwell | Phi @ LV |
| 32 | JaMycal Hasty | SF vs Ind |
| 33 | Nyheim Hines | Ind @ SF |
| 34 | David Johnson | Hou @ Ari |
| 35 | Rhamondre Stevenson | NE vs NYJ |
| 36 | Le'Veon Bell | Bal vs Cin |
| 37 | Kenyan Drake | LV vs Phi |
| 38 | Rashaad Penny | Sea vs NO |
| 39 | Salvon Ahmed | Mia vs Atl |
| 40 | Jerick McKinnon | KC @ Ten |
