All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 10:33 AM ET.
| Rank | Player | Match |
| 1 | Derrick Henry | Ten vs Buf |
| 2 | Kareem Hunt | Cle vs Ari |
| 3 | Davante Adams | GB @ Chi |
| 4 | Dalvin Cook | Min @ Car |
| 5 | Tyreek Hill (GTD) | KC @ Wsh |
| 6 | Austin Ekeler | LAC @ Bal |
| 7 | Joe Mixon | Cin @ Det |
| 8 | Stefon Diggs | Buf @ Ten |
| 9 | Cooper Kupp | LAR @ NYG |
| 10 | Aaron Jones | GB @ Chi |
| 11 | Jonathan Taylor | Ind vs Hou |
| 12 | Ezekiel Elliott | Dal @ NE |
| 13 | Najee Harris | Pit vs Sea |
| 14 | Travis Kelce | KC @ Wsh |
| 15 | D'Andre Swift | Det vs Cin |
| 16 | Darrell Henderson | LAR @ NYG |
| 17 | D.J. Moore | Car vs Min |
| 18 | Antonio Gibson | Wsh vs KC |
| 19 | DeAndre Hopkins | Ari @ Cle |
| 20 | Ja'Marr Chase | Cin @ Det |
| 21 | Terry McLaurin (GTD) | Wsh vs KC |
| 22 | Mike Williams | LAC @ Bal |
| 23 | Justin Jefferson | Min @ Car |
| 24 | A.J. Brown | Ten vs Buf |
| 25 | CeeDee Lamb | Dal @ NE |
| 26 | Amari Cooper | Dal @ NE |
| 27 | Khalil Herbert | Chi vs GB |
| 28 | Chuba Hubbard | Car vs Min |
| 29 | D.K. Metcalf | Sea @ Pit |
| 30 | Mark Andrews | Bal vs LAC |
| 31 | Robert Woods | LAR @ NYG |
| 32 | Josh Jacobs | LV @ Den |
| 33 | Keenan Allen | LAC @ Bal |
| 34 | Darren Waller | LV @ Den |
| 35 | Brandin Cooks | Hou @ Ind |
| Rank | Player | Match |
| 36 | Marquise Brown | Bal vs LAC |
| 37 | Courtland Sutton | Den vs LV |
| 38 | Diontae Johnson | Pit vs Sea |
| 39 | Tyler Lockett | Sea @ Pit |
| 40 | Tee Higgins | Cin @ Det |
| 41 | Chase Claypool | Pit vs Sea |
| 42 | Jakobi Meyers | NE vs Dal |
| 43 | Adam Thielen | Min @ Car |
| 44 | Michael Pittman Jr. | Ind vs Hou |
| 45 | Devontae Booker | NYG vs LAR |
| 46 | Melvin Gordon | Den vs LV |
| 47 | Darrel Williams | KC @ Wsh |
| 48 | Javonte Williams | Den vs LV |
| 49 | Allen Robinson | Chi vs GB |
| 50 | Julio Jones (GTD) | Ten vs Buf |
| 51 | Chase Edmonds | Ari @ Cle |
| 52 | Tyler Boyd | Cin @ Det |
| 53 | Cole Beasley | Buf @ Ten |
| 54 | Zack Moss | Buf @ Ten |
| 55 | Odell Beckham | Cle vs Ari |
| 56 | Kadarius Toney | NYG vs LAR |
| 57 | Jamaal Williams | Det vs Cin |
| 58 | Darnell Mooney | Chi vs GB |
| 59 | Sterling Shepard | NYG vs LAR |
| 60 | T.J. Hockenson | Det vs Cin |
| 61 | Robby Anderson | Car vs Min |
| 62 | Emmanuel Sanders | Buf @ Ten |
| 63 | Damien Harris | NE vs Dal |
| 64 | Devin Singletary | Buf @ Ten |
| 65 | Hunter Renfrow | LV @ Den |
| 66 | Latavius Murray | Bal vs LAC |
| 67 | Noah Fant | Den vs LV |
| 68 | Dalton Schultz | Dal @ NE |
| 69 | Mecole Hardman | KC @ Wsh |
| 70 | Tim Patrick | Den vs LV |
