All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 9:10 AM ET.
| Rank | Player | Match |
| 1 | Derrick Henry | Ten @ NYJ |
| 2 | Alvin Kamara | NO vs NYG |
| 3 | Dalvin Cook (GTD) | Min vs Cle |
| 4 | Aaron Jones | GB vs Pit |
| 5 | Austin Ekeler | LAC vs LV |
| 6 | David Montgomery | Chi vs Det |
| 7 | Najee Harris | Pit @ GB |
| 8 | Ezekiel Elliott | Dal vs Car |
| 9 | D'Andre Swift | Det @ Chi |
| 10 | Saquon Barkley | NYG @ NO |
| 11 | Antonio Gibson | Wsh @ Atl |
| 12 | Nick Chubb | Cle @ Min |
| 13 | Chuba Hubbard | Car @ Dal |
| 14 | Jonathan Taylor | Ind @ Mia |
| 15 | Chris Carson | Sea @ SF |
| 16 | Clyde Edwards-Helaire | KC @ Phi |
| 17 | Miles Sanders | Phi vs KC |
| 18 | Leonard Fournette | TB @ NE |
| 19 | Mike Davis | Atl vs Wsh |
| 20 | Myles Gaskin | Mia vs Ind |
| Rank | Player | Match |
| 21 | Chase Edmonds | Ari @ LAR |
| 22 | Kareem Hunt | Cle @ Min |
| 23 | Darrell Henderson | LAR vs Ari |
| 24 | Melvin Gordon | Den vs Bal |
| 25 | Michael Carter | NYJ vs Ten |
| 26 | Javonte Williams | Den vs Bal |
| 27 | Devin Singletary | Buf vs Hou |
| 28 | Zack Moss | Buf vs Hou |
| 29 | Jamaal Williams | Det @ Chi |
| 30 | Kenyan Drake | LV @ LAC |
| 31 | Tony Pollard | Dal vs Car |
| 32 | Nyheim Hines | Ind @ Mia |
| 33 | Sony Michel | LAR vs Ari |
| 34 | Damien Harris | NE vs TB |
| 35 | Trey Sermon | SF vs Sea |
| 36 | Eli Mitchell (Out) | SF vs Sea |
| 37 | J.D. McKissic | Wsh @ Atl |
| 38 | Josh Jacobs | LV @ LAC |
| 39 | James Conner | Ari @ LAR |
| 40 | Ty'Son Williams | Bal @ Den |
