All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 10:08 AM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | Car vs NO |
| 2 | Alvin Kamara | NO @ Car |
| 3 | Dalvin Cook | Min @ Ari |
| 4 | Nick Chubb | Cle vs Hou |
| 5 | Aaron Jones | GB vs Det |
| 6 | Derrick Henry | Ten @ Sea |
| 7 | Chris Carson | Sea vs Ten |
| 8 | Austin Ekeler (GTD) | LAC vs Dal |
| 9 | Najee Harris | Pit vs LV |
| 10 | Joe Mixon | Cin @ Chi |
| 11 | Jonathan Taylor | Ind vs LAR |
| 12 | David Montgomery | Chi vs Cin |
| 13 | Ezekiel Elliott | Dal @ LAC |
| 14 | Clyde Edwards-Helaire | KC @ Bal |
| 15 | D'Andre Swift | Det @ GB |
| 16 | Darrell Henderson (GTD) | LAR @ Ind |
| 17 | Miles Sanders | Phi vs SF |
| 18 | Damien Harris | NE @ NYJ |
| 19 | Chase Edmonds | Ari vs Min |
| 20 | Myles Gaskin | Mia vs Buf |
| Rank | Player | Match |
| 21 | Kenyan Drake | LV @ Pit |
| 22 | Melvin Gordon (GTD) | Den @ Jax |
| 23 | Mike Davis | Atl @ TB |
| 24 | James Robinson | Jax vs Den |
| 25 | Kareem Hunt | Cle vs Hou |
| 26 | Eli Mitchell | SF @ Phi |
| 27 | Javonte Williams | Den @ Jax |
| 28 | Leonard Fournette | TB vs Atl |
| 29 | Ty'Son Williams | Bal vs KC |
| 30 | Devin Singletary | Buf @ Mia |
| 31 | James White | NE @ NYJ |
| 32 | Nyheim Hines | Ind vs LAR |
| 33 | Jamaal Williams | Det @ GB |
| 34 | Ronald Jones | TB vs Atl |
| 35 | James Conner | Ari vs Min |
| 36 | Damien Williams | Chi vs Cin |
| 37 | A.J. Dillon | GB vs Det |
| 38 | Mark Ingram | Hou @ Cle |
| 39 | Tony Pollard | Dal @ LAC |
| 40 | Carlos Hyde | Jax vs Den |
