All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 9:55 AM ET.
| Rank | Player | Match |
| 1 | Derrick Henry | Ten vs Det |
| 2 | Dalvin Cook | Min vs Chi |
| 3 | Alvin Kamara | NO vs KC |
| 4 | Jonathan Taylor | Ind vs Hou |
| 5 | Nick Chubb | Cle @ NYG |
| 6 | James Robinson | Jax @ Bal |
| 7 | Miles Sanders | Phi @ Ari |
| 8 | Cam Akers (GTD) | LAR vs NYJ |
| 9 | Chris Carson | Sea @ Wsh |
| 10 | David Montgomery | Chi @ Min |
| 11 | James Conner | Pit @ Cin |
| 12 | Kenyan Drake | Ari vs Phi |
| 13 | D'Andre Swift (GTD) | Det @ Ten |
| 14 | Ezekiel Elliott (GTD) | Dal vs SF |
| 15 | J.K. Dobbins | Bal vs Jax |
| 16 | Clyde Edwards-Helaire | KC @ NO |
| 17 | Leonard Fournette | TB @ Atl |
| 18 | Joe Mixon (GTD) | Cin vs Pit |
| 19 | David Johnson | Hou @ Ind |
| 20 | Wayne Gallman | NYG vs Cle |
| Rank | Player | Match |
| 21 | Raheem Mostert (GTD) | SF @ Dal |
| 22 | J.D. McKissic | Wsh vs Sea |
| 23 | Kareem Hunt | Cle @ NYG |
| 24 | Nyheim Hines | Ind vs Hou |
| 25 | Salvon Ahmed (GTD) | Mia vs NE |
| 26 | La'Mical Perine (GTD) | NYJ @ LAR |
| 27 | Jeff Wilson | SF @ Dal |
| 28 | Chase Edmonds (que) | Ari vs Phi |
| 29 | Todd Gurley (GTD) | Atl vs TB |
| 30 | Latavius Murray | NO vs KC |
| 31 | James White (que) | NE @ Mia |
| 32 | Peyton Barber | Wsh vs Sea |
| 33 | Sony Michel | NE @ Mia |
| 34 | Gus Edwards | Bal vs Jax |
| 35 | Tony Pollard | Dal vs SF |
| 36 | Ito Smith (GTD) | Atl vs TB |
| 37 | DeAndre Washington | Mia vs NE |
| 38 | Carlos Hyde | Sea @ Wsh |
| 39 | LeSean McCoy | TB @ Atl |
| 40 | Le'Veon Bell | KC @ NO |
