All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 7:55 AM ET.
| Rank | Player | Match |
| 1 | Derrick Henry | Ten @ Jax |
| 2 | Davante Adams | GB @ Det |
| 3 | Dalvin Cook | Min @ TB |
| 4 | Aaron Jones | GB @ Det |
| 5 | Austin Ekeler | LAC vs Atl |
| 6 | James Robinson | Jax vs Ten |
| 7 | D.K. Metcalf | Sea vs NYJ |
| 8 | Tyreek Hill | KC @ Mia |
| 9 | Calvin Ridley | Atl @ LAC |
| 10 | Chris Carson | Sea vs NYJ |
| 11 | Alvin Kamara | NO @ Phi |
| 12 | Tyler Lockett | Sea vs NYJ |
| 13 | Travis Kelce | KC @ Mia |
| 14 | DeAndre Hopkins (que) | Ari @ NYG |
| 15 | Keenan Allen | LAC vs Atl |
| 16 | Stefon Diggs | Buf vs Pit |
| 17 | Mike Davis | Car vs Den |
| 18 | David Montgomery | Chi vs Hou |
| 19 | Adam Thielen | Min @ TB |
| 20 | Ezekiel Elliott (GTD) | Dal @ Cin |
| 21 | Nick Chubb | Cle vs Bal |
| 22 | A.J. Brown | Ten @ Jax |
| 23 | Terry McLaurin | Wsh @ SF |
| 24 | Robby Anderson | Car vs Den |
| 25 | Justin Jefferson | Min @ TB |
| 26 | Allen Robinson (GTD) | Chi vs Hou |
| 27 | James Conner | Pit @ Buf |
| 28 | Michael Thomas | NO @ Phi |
| 29 | Diontae Johnson | Pit @ Buf |
| 30 | Chris Godwin | TB vs Min |
| 31 | Darren Waller | LV vs Ind |
| 32 | Brandin Cooks (que) | Hou @ Chi |
| 33 | Ronald Jones | TB vs Min |
| 34 | Jonathan Taylor | Ind @ LV |
| 35 | Marvin Jones | Det vs GB |
| Rank | Player | Match |
| 36 | Mike Evans | TB vs Min |
| 37 | Kenyan Drake (que) | Ari @ NYG |
| 38 | Duke Johnson | Hou @ Chi |
| 39 | Wayne Gallman | NYG vs Ari |
| 40 | Raheem Mostert | SF vs Wsh |
| 41 | Corey Davis | Ten @ Jax |
| 42 | Josh Jacobs (GTD) | LV vs Ind |
| 43 | D'Andre Swift (GTD) | Det vs GB |
| 44 | Clyde Edwards-Helaire | KC @ Mia |
| 45 | Amari Cooper | Dal @ Cin |
| 46 | Miles Sanders | Phi vs NO |
| 47 | Deebo Samuel | SF vs Wsh |
| 48 | DeVante Parker | Mia vs KC |
| 49 | Jarvis Landry | Cle vs Bal |
| 50 | Giovani Bernard | Cin vs Dal |
| 51 | J.D. McKissic | Wsh @ SF |
| 52 | Todd Gurley (GTD) | Atl @ LAC |
| 53 | Melvin Gordon | Den @ Car |
| 54 | JuJu Smith-Schuster (GTD) | Pit @ Buf |
| 55 | Cole Beasley | Buf vs Pit |
| 56 | Brandon Aiyuk | SF vs Wsh |
| 57 | D.J. Chark | Jax vs Ten |
| 58 | Kareem Hunt | Cle vs Bal |
| 59 | Curtis Samuel | Car vs Den |
| 60 | Tee Higgins (GTD) | Cin vs Dal |
| 61 | Antonio Brown | TB vs Min |
| 62 | Mark Andrews | Bal @ Cle |
| 63 | Nyheim Hines | Ind @ LV |
| 64 | T.J. Hockenson | Det vs GB |
| 65 | Tyler Boyd | Cin vs Dal |
| 66 | Chase Claypool | Pit @ Buf |
| 67 | DeAndre Washington | Mia vs KC |
| 68 | Mike Williams | LAC vs Atl |
| 69 | Jamison Crowder (GTD) | NYJ @ Sea |
| 70 | T.Y. Hilton (GTD) | Ind @ LV |
