All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 3:40 AM ET.
| Rank | Player | Match |
| 1 | Dalvin Cook | Min vs Jax |
| 2 | Derrick Henry | Ten vs Cle |
| 3 | Davante Adams | GB vs Phi |
| 4 | Tyreek Hill | KC vs Den |
| 5 | D.K. Metcalf | Sea vs NYG |
| 6 | Austin Ekeler | LAC vs NE |
| 7 | James Robinson | Jax @ Min |
| 8 | Aaron Jones | GB vs Phi |
| 9 | Keenan Allen | LAC vs NE |
| 10 | DeAndre Hopkins | Ari vs LAR |
| 11 | Travis Kelce | KC vs Den |
| 12 | Myles Gaskin (GTD) | Mia vs Cin |
| 13 | Tyler Lockett | Sea vs NYG |
| 14 | Adam Thielen | Min vs Jax |
| 15 | A.J. Brown | Ten vs Cle |
| 16 | Michael Thomas | NO @ Atl |
| 17 | Alvin Kamara | NO @ Atl |
| 18 | Stefon Diggs | Buf @ SF |
| 19 | Calvin Ridley | Atl vs NO |
| 20 | Miles Sanders | Phi @ GB |
| 21 | Allen Robinson (GTD) | Chi vs Det |
| 22 | Justin Jefferson | Min vs Jax |
| 23 | Robert Woods | LAR @ Ari |
| 24 | Nick Chubb | Cle @ Ten |
| 25 | Darren Waller | LV @ NYJ |
| 26 | Chris Carson | Sea vs NYG |
| 27 | Brandin Cooks | Hou vs Ind |
| 28 | Devontae Booker | LV @ NYJ |
| 29 | Raheem Mostert | SF vs Buf |
| 30 | Clyde Edwards-Helaire | KC vs Den |
| 31 | Julio Jones (GTD) | Atl vs NO |
| 32 | Terry McLaurin (que) | Wsh @ Pit |
| 33 | David Montgomery (GTD) | Chi vs Det |
| 34 | Cooper Kupp | LAR @ Ari |
| 35 | Antonio Gibson | Wsh @ Pit |
| Rank | Player | Match |
| 36 | Deebo Samuel | SF vs Buf |
| 37 | DeVante Parker | Mia vs Cin |
| 38 | Diontae Johnson | Pit vs Wsh |
| 39 | Wayne Gallman | NYG @ Sea |
| 40 | JuJu Smith-Schuster (GTD) | Pit vs Wsh |
| 41 | Marvin Jones | Det @ Chi |
| 42 | Chase Claypool | Pit vs Wsh |
| 43 | Kenyan Drake | Ari vs LAR |
| 44 | David Johnson (GTD) | Hou vs Ind |
| 45 | Jarvis Landry | Cle @ Ten |
| 46 | D.J. Chark | Jax @ Min |
| 47 | Jonathan Taylor | Ind @ Hou |
| 48 | Kareem Hunt | Cle @ Ten |
| 49 | Corey Davis | Ten vs Cle |
| 50 | Damien Harris | NE @ LAC |
| 51 | Giovani Bernard | Cin @ Mia |
| 52 | Michael Pittman Jr. | Ind @ Hou |
| 53 | Nyheim Hines | Ind @ Hou |
| 54 | Jerry Jeudy (GTD) | Den @ KC |
| 55 | Denzel Mims | NYJ vs LV |
| 56 | Mike Williams | LAC vs NE |
| 57 | Jamison Crowder (GTD) | NYJ vs LV |
| 58 | Tee Higgins | Cin @ Mia |
| 59 | Brandon Aiyuk | SF vs Buf |
| 60 | Sammy Watkins | KC vs Den |
| 61 | Jakobi Meyers | NE @ LAC |
| 62 | Breshad Perriman | NYJ vs LV |
| 63 | T.J. Hockenson | Det @ Chi |
| 64 | Frank Gore | NYJ vs LV |
| 65 | Darius Slayton | NYG @ Sea |
| 66 | Sterling Shepard | NYG @ Sea |
| 67 | T.Y. Hilton (GTD) | Ind @ Hou |
| 68 | Todd Gurley (GTD) | Atl vs NO |
| 69 | Cole Beasley | Buf @ SF |
| 70 | Hunter Henry | LAC vs NE |
