All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 1:59 PM ET.
| Rank | Player | Match |
| 1 | Ezekiel Elliott | Dal vs Ari |
| 2 | Derrick Henry | Ten vs Hou |
| 3 | Kareem Hunt | Cle @ Pit |
| 4 | Alexander Mattison | Min vs Atl |
| 5 | Aaron Jones | GB @ TB |
| 6 | DeAndre Hopkins | Ari @ Dal |
| 7 | Mike Davis | Car vs Chi |
| 8 | Davante Adams | GB @ TB |
| 9 | Miles Sanders | Phi vs Bal |
| 10 | Clyde Edwards-Helaire | KC @ Buf |
| 11 | Tyreek Hill | KC @ Buf |
| 12 | Adam Thielen | Min vs Atl |
| 13 | Jonathan Taylor | Ind vs Cin |
| 14 | David Montgomery | Chi @ Car |
| 15 | James Robinson | Jax vs Det |
| 16 | James Conner | Pit vs Cle |
| 17 | Joe Mixon | Cin @ Ind |
| 18 | Travis Kelce | KC @ Buf |
| 19 | Calvin Ridley | Atl @ Min |
| 20 | Allen Robinson | Chi @ Car |
| 21 | Stefon Diggs | Buf vs KC |
| 22 | George Kittle | SF vs LAR |
| 23 | Kenny Golladay | Det @ Jax |
| 24 | Todd Gurley | Atl @ Min |
| 25 | A.J. Brown | Ten vs Hou |
| 26 | Raheem Mostert | SF vs LAR |
| 27 | Myles Gaskin | Mia vs NYJ |
| 28 | Mike Evans (GTD) | TB vs GB |
| 29 | Chris Godwin (GTD) | TB vs GB |
| 30 | Terry McLaurin | Wsh @ NYG |
| 31 | Ronald Jones | TB vs GB |
| 32 | Amari Cooper | Dal vs Ari |
| 33 | Julio Jones | Atl @ Min |
| 34 | Robby Anderson | Car vs Chi |
| 35 | David Johnson | Hou @ Ten |
| Rank | Player | Match |
| 36 | Odell Beckham | Cle @ Pit |
| 37 | Antonio Gibson | Wsh @ NYG |
| 38 | Cooper Kupp | LAR @ SF |
| 39 | Jamison Crowder | NYJ @ Mia |
| 40 | Devin Singletary | Buf vs KC |
| 41 | Marquise Brown | Bal @ Phi |
| 42 | Will Fuller | Hou @ Ten |
| 43 | Robert Woods | LAR @ SF |
| 44 | Kenyan Drake | Ari @ Dal |
| 45 | D.J. Moore | Car vs Chi |
| 46 | Mark Andrews | Bal @ Phi |
| 47 | Devonta Freeman | NYG vs Wsh |
| 48 | DeVante Parker | Mia vs NYJ |
| 49 | Darius Slayton (que) | NYG vs Wsh |
| 50 | CeeDee Lamb | Dal vs Ari |
| 51 | Tyler Boyd | Cin @ Ind |
| 52 | JuJu Smith-Schuster | Pit vs Cle |
| 53 | Deebo Samuel | SF vs LAR |
| 54 | T.Y. Hilton | Ind vs Cin |
| 55 | Chase Claypool | Pit vs Cle |
| 56 | Justin Jefferson | Min vs Atl |
| 57 | Laviska Shenault | Jax vs Det |
| 58 | Tee Higgins | Cin @ Ind |
| 59 | Darrell Henderson | LAR @ SF |
| 60 | Marvin Jones | Det @ Jax |
| 61 | Jonnu Smith | Ten vs Hou |
| 62 | Zach Ertz | Phi vs Bal |
| 63 | Brandin Cooks | Hou @ Ten |
| 64 | Adrian Peterson | Det @ Jax |
| 65 | D.J. Chark (que) | Jax vs Det |
| 66 | Evan Engram | NYG vs Wsh |
| 67 | Michael Gallup | Dal vs Ari |
| 68 | T.J. Hockenson | Det @ Jax |
| 69 | Golden Tate | NYG vs Wsh |
| 70 | Travis Fulgham | Phi vs Bal |
