All position rankings are: QB | RB | WR | TE | FLEX | D
These rankings were updated as of Sun 8:40 AM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | Car @ NO |
| 2 | Alvin Kamara | NO vs Car |
| 3 | Michael Thomas | NO vs Car |
| 4 | Nick Chubb | Cle vs Mia |
| 5 | Julio Jones | Atl vs TB |
| 6 | Saquon Barkley | NYG @ Chi |
| 7 | Leonard Fournette | Jax @ Ten |
| 8 | Derrick Henry | Ten vs Jax |
| 9 | Ezekiel Elliott | Dal @ NE |
| 10 | Mike Evans | TB @ Atl |
| 11 | Davante Adams | GB @ SF |
| 12 | Le'Veon Bell | NYJ vs Oak |
| 13 | Chris Carson | Sea @ Phi |
| 14 | Josh Jacobs | Oak @ NYJ |
| 15 | Chris Godwin | TB @ Atl |
| 16 | Aaron Jones | GB @ SF |
| 17 | Odell Beckham | Cle vs Mia |
| 18 | Tyler Lockett (GTD) | Sea @ Phi |
| 19 | Julian Edelman (que) | NE vs Dal |
| 20 | Todd Gurley | LAR vs Bal |
| 21 | Tevin Coleman | SF vs GB |
| 22 | Cooper Kupp | LAR vs Bal |
| 23 | Calvin Ridley | Atl vs TB |
| 24 | Jaylen Samuels | Pit @ Cin |
| 25 | Amari Cooper | Dal @ NE |
| 26 | David Montgomery | Chi vs NYG |
| 27 | D.J. Chark | Jax @ Ten |
| 28 | George Kittle (que) | SF vs GB |
| 29 | Phillip Lindsay | Den @ Buf |
| 30 | Jarvis Landry | Cle vs Mia |
| 31 | Zach Ertz | Phi vs Sea |
| 32 | Brian Hill | Atl vs TB |
| 33 | Mark Ingram | Bal @ LAR |
| 34 | Allen Robinson | Chi vs NYG |
| 35 | D.J. Moore | Car @ NO |
| Rank | Player | Match |
| 36 | Joe Mixon | Cin vs Pit |
| 37 | Devin Singletary | Buf vs Den |
| 38 | Mark Andrews | Bal @ LAR |
| 39 | Courtland Sutton | Den @ Buf |
| 40 | James White | NE vs Dal |
| 41 | Kenny Golladay | Det @ Wsh |
| 42 | DeVante Parker | Mia @ Cle |
| 43 | Kareem Hunt | Cle vs Mia |
| 44 | Jamison Crowder | NYJ vs Oak |
| 45 | Sony Michel | NE vs Dal |
| 46 | John Brown | Buf vs Den |
| 47 | D.K. Metcalf | Sea @ Phi |
| 48 | Miles Sanders | Phi vs Sea |
| 49 | Emmanuel Sanders (que) | SF vs GB |
| 50 | Darren Waller | Oak @ NYJ |
| 51 | Robert Woods | LAR vs Bal |
| 52 | Alshon Jeffery (que) | Phi vs Sea |
| 53 | Tyrell Williams | Oak @ NYJ |
| 54 | Michael Gallup | Dal @ NE |
| 55 | Golden Tate | NYG @ Chi |
| 56 | Terry McLaurin | Wsh vs Det |
| 57 | Tyler Boyd | Cin vs Pit |
| 58 | Marvin Jones | Det @ Wsh |
| 59 | Ronald Jones | TB @ Atl |
| 60 | Curtis Samuel | Car @ NO |
| 61 | Brandin Cooks | LAR vs Bal |
| 62 | Deebo Samuel (que) | SF vs GB |
| 63 | Jamaal Williams | GB @ SF |
| 64 | Marquise Brown | Bal @ LAR |
| 65 | Dede Westbrook | Jax @ Ten |
| 66 | Tarik Cohen | Chi vs NYG |
| 67 | Sterling Shepard | NYG @ Chi |
| 68 | Kalen Ballage | Mia @ Cle |
| 69 | Latavius Murray | NO vs Car |
| 70 | Diontae Johnson | Pit @ Cin |
