All position rankings are: QB | RB | WR | TE | FLEX | D
These rankings were updated as of Sat 2:38 PM ET.
| Rank | Player | Match |
| 1 | Saquon Barkley | NYG vs Ari |
| 2 | Leonard Fournette | Jax @ Cin |
| 3 | Ezekiel Elliott | Dal vs Phi |
| 4 | Dalvin Cook | Min @ Det |
| 5 | David Johnson (que) | Ari @ NYG |
| 6 | Chris Carson | Sea vs Bal |
| 7 | Le'Veon Bell | NYJ vs NE |
| 8 | Julio Jones (GTD) | Atl vs LAR |
| 9 | DeAndre Hopkins | Hou @ Ind |
| 10 | Cooper Kupp | LAR @ Atl |
| 11 | Michael Thomas | NO @ Chi |
| 12 | Derrick Henry | Ten vs LAC |
| 13 | Aaron Jones | GB vs Oak |
| 14 | Julian Edelman (que) | NE @ NYJ |
| 15 | Marlon Mack | Ind vs Hou |
| 16 | Kerryon Johnson | Det vs Min |
| 17 | Todd Gurley | LAR @ Atl |
| 18 | Tyler Lockett | Sea vs Bal |
| 19 | T.Y. Hilton | Ind vs Hou |
| 20 | Devonta Freeman | Atl vs LAR |
| 21 | Evan Engram | NYG vs Ari |
| 22 | Keenan Allen | LAC @ Ten |
| 23 | George Kittle (GTD) | SF @ Wsh |
| 24 | Josh Jacobs (GTD) | Oak @ GB |
| 25 | Mark Ingram | Bal @ Sea |
| 26 | Adam Thielen | Min @ Det |
| 27 | Kenny Golladay | Det vs Min |
| 28 | Zach Ertz | Phi @ Dal |
| 29 | Robert Woods | LAR @ Atl |
| 30 | Tevin Coleman | SF @ Wsh |
| 31 | Melvin Gordon | LAC @ Ten |
| 32 | Tyler Boyd | Cin vs Jax |
| 33 | Amari Cooper (que) | Dal vs Phi |
| 34 | Michael Gallup | Dal vs Phi |
| 35 | D.J. Chark | Jax @ Cin |
| Rank | Player | Match |
| 36 | Alshon Jeffery | Phi @ Dal |
| 37 | Sony Michel | NE @ NYJ |
| 38 | Allen Robinson | Chi vs NO |
| 39 | Stefon Diggs | Min @ Det |
| 40 | Terry McLaurin | Wsh vs SF |
| 41 | Austin Hooper | Atl vs LAR |
| 42 | David Montgomery | Chi vs NO |
| 43 | Mark Andrews | Bal @ Sea |
| 44 | Larry Fitzgerald | Ari @ NYG |
| 45 | Darren Waller (GTD) | Oak @ GB |
| 46 | Latavius Murray | NO @ Chi |
| 47 | Joe Mixon | Cin vs Jax |
| 48 | Austin Ekeler | LAC @ Ten |
| 49 | John Brown (GTD) | Buf vs Mia |
| 50 | Will Fuller | Hou @ Ind |
| 51 | Brandin Cooks (GTD) | LAR @ Atl |
| 52 | Golden Tate | NYG vs Ari |
| 53 | Carlos Hyde | Hou @ Ind |
| 54 | Matt Breida | SF @ Wsh |
| 55 | James White | NE @ NYJ |
| 56 | Dede Westbrook (que) | Jax @ Cin |
| 57 | Calvin Ridley | Atl vs LAR |
| 58 | Devin Singletary | Buf vs Mia |
| 59 | Frank Gore | Buf vs Mia |
| 60 | Kenyan Drake | Mia @ Buf |
| 61 | D.K. Metcalf | Sea vs Bal |
| 62 | Jamaal Williams | GB vs Oak |
| 63 | Hunter Henry | LAC @ Ten |
| 64 | Mike Williams (GTD) | LAC @ Ten |
| 65 | Jamison Crowder | NYJ vs NE |
| 66 | Phillip Dorsett (que) | NE @ NYJ |
| 67 | Jordan Howard | Phi @ Dal |
| 68 | Marvin Jones | Det vs Min |
| 69 | Christian Kirk (que) | Ari @ NYG |
| 70 | Mohamed Sanu | Atl vs LAR |
