Other position ranks are: Top-25 QBs Top-40 RBs Top-50 WRs Top-25 TEs
These rankings were updated as of Wed 5:20 PM ET.
| Rank | Player | Match |
| 1 | Ezekiel Elliott | Dal vs Sea |
| 2 | DeAndre Hopkins | Hou vs Ind |
| 3 | Melvin Gordon (GTD) | LAC @ Bal |
| 4 | T.Y. Hilton (GTD) | Ind @ Hou |
| 5 | Chris Carson | Sea @ Dal |
| 6 | Keenan Allen | LAC @ Bal |
| 7 | Zach Ertz | Phi @ Chi |
| 8 | Eric Ebron | Ind @ Hou |
| 9 | Marlon Mack | Ind @ Hou |
| 10 | Amari Cooper | Dal vs Sea |
| 11 | Tarik Cohen | Chi vs Phi |
| 12 | Doug Baldwin | Sea @ Dal |
| 13 | Lamar Miller | Hou vs Ind |
| 14 | Tyler Lockett | Sea @ Dal |
| 15 | Alshon Jeffery | Phi @ Chi |
| 16 | Jordan Howard | Chi vs Phi |
| 17 | Gus Edwards | Bal vs LAC |
| 18 | Josh Adams | Phi @ Chi |
| 19 | Austin Ekeler | LAC @ Bal |
| 20 | Allen Robinson (GTD) | Chi vs Phi |
| 21 | Dontrelle Inman | Ind @ Hou |
| 22 | Darren Sproles | Phi @ Chi |
| 23 | Kenneth Dixon | Bal vs LAC |
| 24 | Mike Williams | LAC @ Bal |
| 25 | Taylor Gabriel | Chi vs Phi |
| 26 | Nelson Agholor | Phi @ Chi |
| 27 | Trey Burton | Chi vs Phi |
| 28 | Golden Tate | Phi @ Chi |
| 29 | Nyheim Hines | Ind @ Hou |
| 30 | Tyrell Williams | LAC @ Bal |
| 31 | Cole Beasley | Dal vs Sea |
| 32 | DeAndre Carter | Hou vs Ind |
| 33 | Michael Gallup | Dal vs Sea |
| 34 | Keke Coutee (GTD) | Hou vs Ind |
| 35 | John Brown | Bal vs LAC |
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| Rank | Player | Match |
| 36 | Blake Jarwin | Dal vs Sea |
| 37 | Wendell Smallwood | Phi @ Chi |
| 38 | Michael Crabtree | Bal vs LAC |
| 39 | Mike Davis | Sea @ Dal |
| 40 | David Moore | Sea @ Dal |
| 41 | Willie Snead | Bal vs LAC |
| 42 | Anthony Miller (GTD) | Chi vs Phi |
| 43 | Alfred Blue | Hou vs Ind |
| 44 | Hunter Henry (Q) | LAC @ Bal |
| 45 | Mark Andrews | Bal vs LAC |
| 46 | Chester Rogers | Ind @ Hou |
| 47 | Rod Smith | Dal vs Sea |
| 48 | Rashaad Penny | Sea @ Dal |
| 49 | Vyncint Smith | Hou vs Ind |
| 50 | Jordan Thomas | Hou vs Ind |
| 51 | Nick Vannett | Sea @ Dal |
| 52 | Justin Jackson | LAC @ Bal |
| 53 | Ty Montgomery | Bal vs LAC |
| 54 | Ryan Griffin | Hou vs Ind |
| 55 | Dallas Goedert | Phi @ Chi |
| 56 | Travis Benjamin | LAC @ Bal |
| 57 | Kevin White | Chi vs Phi |
| 58 | Hayden Hurst | Bal vs LAC |
| 59 | D'Onta Foreman | Hou vs Ind |
| 60 | Ryan Grant | Ind @ Hou |
| 61 | Ed Dickson | Sea @ Dal |
| 62 | Allen Hurns | Dal vs Sea |
| 63 | Antonio Gates | LAC @ Bal |
| 64 | Jordan Matthews | Phi @ Chi |
| 65 | Javon Wims | Chi vs Phi |
| 66 | Mo Alie-Cox | Ind @ Hou |
| 67 | Jordan Akins | Hou vs Ind |
| 68 | Zach Pascal | Ind @ Hou |
| 69 | Jaron Brown | Sea @ Dal |
| 70 | Virgil Green | LAC @ Bal |
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