These standard ranks are updated as of Sept. 28.
Other Week 4 Ranks: Top 25 QBs || Top 50 WRs || Top 25 TEs
Build the best lineups with the power of The Machine for Daily Fantasy Sports.
| Rank | Player | Team | Opp |
| 1 | Alvin Kamara | NO | @NYG |
| 2 | Ezekiel Elliott | DAL | DET |
| 3 | Saquon Barkley | NYG | NO |
| 4 | Melvin Gordon | LAC | SF |
| 5 | Leonard Fournette* | JAX | NYJ |
| 6 | James Conner | PIT | BAL |
| 7 | Jordan Howard | CHI | TB |
| 8 | Tevin Coleman | ATL | CIN |
| 9 | Kareem Hunt | KC | @DEN |
| 10 | Giovani Bernard | CIN | @ATL |
| 11 | Lamar Miller | HOU | @IND |
| 12 | Carlos Hyde | CLE | @OAK |
| 13 | Kenyan Drake | MIA | @NE |
| 14 | Marshawn Lynch | OAK | CLE |
| 15 | David Johnson | ARI | SEA |
| 16 | Alex Collins | BAL | DEN |
| 17 | Chris Carson | SEA | @ARI |
| 18 | James White | NE | MIA |
| 19 | LeSean McCoy* | BUF | @GB |
| 20 | Royce Freeman | DEN | KC |
Build the best lineups with the power of The Machine for Daily Fantasy Sports.
| Rank | Player | Team | Opp |
| 21 | Matt Breida | SF | @LAC |
| 22 | Isaiah Crowell | NYJ | @JAX |
| 23 | Kerryon Johnson | DET | @DAL |
| 24 | Jay Ajayi* | PHI | @TEN |
| 25 | Sony Michel | NE | MIA |
| 26 | Phillip Lindsay | DEN | KC |
| 27 | Dion Lewis | TEN | PHI |
| 28 | Javorius Allen | BAL | @PIT |
| 29 | Bilal Powell | NYJ | @JAX |
| 30 | Alfred Morris | SF | @LAC |
| 31 | Peyton Barber | TB | @CHI |
| 32 | Austin Ekeler | LAC | SF |
| 33 | Aaron Jones | GB | BUF |
| 34 | Derrick Henry | TEN | PHI |
| 35 | Tarik Cohen | CHI | TB |
| 36 | Corey Clement | PHI | @TEN |
| 37 | Frank Gore | MIA | OAK |
| 38 | T.J. Yeldon | JAX | NYJ |
| 39 | Duke Johnson | CLE | @OAK |
| 40 | Jordan Wilkins | IND | HOU |
*Assuming the player plays.
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