All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 12:06 PM ET.
| Rank | Player | Match |
| 1 | Jahmyr Gibbs | Det @ Ari |
| 2 | Bijan Robinson | Atl vs Bal |
| 3 | Jonathan Taylor | Ind @ Pit |
| 4 | Derrick Henry | Bal @ Atl |
| 5 | Kyren Williams | LAR vs Buf |
| 6 | Christian McCaffrey | SF @ Sea |
| 7 | D'Andre Swift | Chi @ GB |
| 8 | Chase Brown | Cin @ Mia |
| 9 | Jaylen Warren | Pit vs Ind |
| 10 | James Cook | Buf @ LAR |
| 11 | Ashton Jeanty (Q) | LV @ NE |
| 12 | Aaron Jones | Min @ NO |
| 13 | Braelon Allen | NYJ vs Cle |
| 14 | Quinshon Judkins | Cle @ NYJ |
| 15 | Jeremiyah Love | Ari vs Det |
| 16 | Cam Skattebo | NYG @ Wsh |
| 17 | Bhayshul Tuten | Jax vs Phi |
| 18 | David Montgomery | Hou @ Ten |
| 19 | Emanuel Wilson | Sea vs SF |
| 20 | Rhamondre Stevenson (Q) | NE vs LV |
| Rank | Player | Match |
| 21 | Jacory Croskey-Merritt | Wsh vs NYG |
| 22 | Tony Pollard | Ten vs Hou |
| 23 | J.K. Dobbins | Den @ LAC |
| 24 | TreVeyon Henderson | NE vs LV |
| 25 | Ollie Gordon | Mia vs Cin |
| 26 | Alvin Kamara (Q) | NO vs Min |
| 27 | Will Shipley | Phi @ Jax |
| 28 | RJ Harvey | Den @ LAC |
| 29 | Keaton Mitchell | LAC vs Den |
| 30 | Omarion Hampton | LAC vs Den |
| 31 | MarShawn Lloyd | GB vs Chi |
| 32 | Tyler Allgeier | Ari vs Det |
| 33 | Woody Marks | Hou @ Ten |
| 34 | Kaleb Johnson | GB vs Chi |
| 35 | Brian Robinson | Atl vs Bal |
| 36 | Blake Corum | LAR vs Buf |
| 37 | Tyjae Spears | Ten vs Hou |
| 38 | George Holani (Q) | Sea vs SF |
| 39 | Mike Washington | LV @ NE |
| 40 | Chris Rodriguez Jr. | Jax vs Phi |
