These rankings were updated as of Thu 12:39 PM ET.
| Rank | Player | Match |
| 1 | Saquon Barkley | Phi vs Dal |
| 2 | Ja'Marr Chase | Cin @ Cle |
| 3 | Bijan Robinson | Atl vs TB |
| 4 | Derrick Henry | Bal @ Buf |
| 5 | Christian McCaffrey | SF @ Sea |
| 6 | De'Von Achane (Q) | Mia @ Ind |
| 7 | Jahmyr Gibbs | Det @ GB |
| 8 | Justin Jefferson (Q) | Min @ Chi |
| 9 | Jonathan Taylor | Ind vs Mia |
| 10 | Brian Thomas Jr. | Jax vs Car |
| 11 | Josh Jacobs | GB vs Det |
| 12 | Malik Nabers | NYG @ Wsh |
| 13 | Chase Brown | Cin @ Cle |
| 14 | Bucky Irving | TB @ Atl |
| 15 | Kyren Williams | LAR vs Hou |
| 16 | CeeDee Lamb | Dal @ Phi |
| 17 | Mike Evans | TB @ Atl |
| 18 | Puka Nacua | LAR vs Hou |
| 19 | A.J. Brown | Phi vs Dal |
| 20 | Ashton Jeanty | LV @ NE |
| 21 | James Conner | Ari @ NO |
| 22 | Tyreek Hill (Q) | Mia @ Ind |
| 23 | Nico Collins | Hou @ LAR |
| 24 | Amon-Ra St. Brown | Det @ GB |
| 25 | Alvin Kamara | NO vs Ari |
| 26 | Drake London | Atl vs TB |
| 27 | Chuba Hubbard | Car @ Jax |
| 28 | Tee Higgins | Cin @ Cle |
| 29 | Terry McLaurin | Wsh vs NYG |
| 30 | Ladd McConkey | LAC vs KC |
| 31 | James Cook | Buf vs Bal |
| 32 | Jaxon Smith-Njigba | Sea vs SF |
| 33 | Kenneth Walker III | Sea vs SF |
| 34 | Davante Adams | LAR vs Hou |
| 35 | Brock Bowers | LV @ NE |
| Rank | Player | Match |
| 36 | Tony Pollard | Ten @ Den |
| 37 | DeVonta Smith | Phi vs Dal |
| 38 | Omarion Hampton | LAC vs KC |
| 39 | Xavier Worthy | KC @ LAC |
| 40 | TreVeyon Henderson | NE vs LV |
| 41 | Jerry Jeudy | Cle vs Cin |
| 42 | D.K. Metcalf | Pit @ NYJ |
| 43 | George Kittle | SF @ Sea |
| 44 | Breece Hall | NYJ vs Pit |
| 45 | Jerome Ford | Cle vs Cin |
| 46 | Trey McBride | Ari @ NO |
| 47 | Aaron Jones | Min @ Chi |
| 48 | Marvin Harrison Jr. | Ari @ NO |
| 49 | Tyrone Tracy Jr. | NYG @ Wsh |
| 50 | Tetairoa McMillan | Car @ Jax |
| 51 | Courtland Sutton | Den vs Ten |
| 52 | DJ Moore | Chi vs Min |
| 53 | Jaylen Warren | Pit @ NYJ |
| 54 | Emeka Egbuka | TB @ Atl |
| 55 | D'Andre Swift | Chi vs Min |
| 56 | Zay Flowers | Bal @ Buf |
| 57 | Jaylen Waddle | Mia @ Ind |
| 58 | Deebo Samuel | Wsh vs NYG |
| 59 | Garrett Wilson | NYJ vs Pit |
| 60 | Isiah Pacheco | KC @ LAC |
| 61 | Cooper Kupp | Sea vs SF |
| 62 | RJ Harvey | Den vs Ten |
| 63 | David Montgomery | Det @ GB |
| 64 | Stefon Diggs | NE vs LV |
| 65 | Calvin Ridley | Ten @ Den |
| 66 | George Pickens | Dal @ Phi |
| 67 | David Njoku | Cle vs Cin |
| 68 | Ricky Pearsall | SF @ Sea |
| 69 | Austin Ekeler | Wsh vs NYG |
| 70 | Mark Andrews | Bal @ Buf |
