All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 1:32 PM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF @ Ari |
| 2 | Kyren Williams | LAR vs Wsh |
| 3 | Alvin Kamara | NO vs NYG |
| 4 | Saquon Barkley | NYG @ NO |
| 5 | Bijan Robinson | Atl @ Car |
| 6 | Rachaad White | TB @ GB |
| 7 | Austin Ekeler | LAC @ LV |
| 8 | Tony Pollard | Dal @ Buf |
| 9 | Jashuan Corbin | NYG @ NO |
| 10 | Jahmyr Gibbs | Det vs Den |
| 11 | Travis Etienne (Q) | Jax vs Bal |
| 12 | Derrick Henry | Ten vs Hou |
| 13 | Joe Mixon | Cin vs Min |
| 14 | Ezekiel Elliott | NE vs KC |
| 15 | Breece Hall (GTD) | NYJ @ Mia |
| 16 | Raheem Mostert (GTD) | Mia vs NYJ |
| 17 | David Montgomery | Det vs Den |
| 18 | Javonte Williams | Den @ Det |
| 19 | De'Von Achane (GTD) | Mia vs NYJ |
| 20 | D'Andre Swift | Phi @ Sea |
| Rank | Player | Match |
| 21 | James Cook | Buf vs Dal |
| 22 | Jerome Ford (GTD) | Cle vs Chi |
| 23 | Chuba Hubbard | Car vs Atl |
| 24 | Zack Moss | Ind vs Pit |
| 25 | James Conner | Ari vs SF |
| 26 | Aaron Jones (GTD) | GB vs TB |
| 27 | Najee Harris | Pit @ Ind |
| 28 | Brian Robinson Jr. (Q) | Wsh @ LAR |
| 29 | Jaylen Warren | Pit @ Ind |
| 30 | Kenneth Walker III | Sea vs Phi |
| 31 | Zamir White | LV vs LAC |
| 32 | Keaton Mitchell | Bal @ Jax |
| 33 | Devin Singletary | Hou @ Ten |
| 34 | Antonio Gibson | Wsh @ LAR |
| 35 | A.J. Dillon (GTD) | GB vs TB |
| 36 | Tyjae Spears | Ten vs Hou |
| 37 | Kareem Hunt (GTD) | Cle vs Chi |
| 38 | Ty Chandler | Min @ Cin |
| 39 | Zach Charbonnet | Sea vs Phi |
| 40 | Jonathan Taylor (GTD) | Ind vs Pit |
