All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 8:39 AM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF vs Sea |
| 2 | Alvin Kamara | NO vs Car |
| 3 | Austin Ekeler | LAC vs Den |
| 4 | Zack Moss | Ind @ Cin |
| 5 | Tony Pollard | Dal vs Phi |
| 6 | Mason Crosby | LAR @ Bal |
| 7 | Bijan Robinson | Atl vs TB |
| 8 | Saquon Barkley | NYG vs GB |
| 9 | Josh Jacobs | LV vs Min |
| 10 | Rachaad White | TB @ Atl |
| 11 | Kyren Williams | LAR @ Bal |
| 12 | Isiah Pacheco (GTD) | KC vs Buf |
| 13 | Joe Mixon | Cin vs Ind |
| 14 | Breece Hall (GTD) | NYJ vs Hou |
| 15 | Travis Etienne (Q) | Jax @ Cle |
| 16 | Raheem Mostert | Mia vs Ten |
| 17 | Jahmyr Gibbs | Det @ Chi |
| 18 | De'Von Achane | Mia vs Ten |
| 19 | Javonte Williams | Den @ LAC |
| 20 | Derrick Henry (GTD) | Ten @ Mia |
| Rank | Player | Match |
| 21 | D'Andre Swift | Phi @ Dal |
| 22 | A.J. Dillon | GB @ NYG |
| 23 | David Montgomery | Det @ Chi |
| 24 | Chuba Hubbard | Car @ NO |
| 25 | Jerome Ford | Cle vs Jax |
| 26 | James Cook | Buf @ KC |
| 27 | Ezekiel Elliott | NE @ Pit |
| 28 | Alexander Mattison | Min @ LV |
| 29 | Najee Harris (GTD) | Pit vs NE |
| 30 | Jaylen Warren | Pit vs NE |
| 31 | Gus Edwards | Bal vs LAR |
| 32 | Devin Singletary | Hou @ NYJ |
| 33 | Keaton Mitchell | Bal vs LAR |
| 34 | Kareem Hunt (Q) | Cle vs Jax |
| 35 | Roschon Johnson | Chi vs Det |
| 36 | Kenneth Walker III (GTD) | Sea @ SF |
| 37 | Khalil Herbert | Chi vs Det |
| 38 | Tyjae Spears | Ten @ Mia |
| 39 | Zach Charbonnet (GTD) | Sea @ SF |
| 40 | Aaron Jones (GTD) | GB @ NYG |
