All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 1:08 PM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF @ Jax |
| 2 | Austin Ekeler | LAC vs Det |
| 3 | Alvin Kamara | NO @ Min |
| 4 | Travis Etienne | Jax vs SF |
| 5 | Nick Chubb | Cle @ Bal |
| 6 | Tony Pollard | Dal vs NYG |
| 7 | Joe Mixon | Cin vs Hou |
| 8 | Derrick Henry | Ten @ TB |
| 9 | Josh Jacobs | LV vs NYJ |
| 10 | Jonathan Taylor | Ind @ NE |
| 11 | Saquon Barkley | NYG @ Dal |
| 12 | Bijan Robinson | Atl @ Ari |
| 13 | Breece Hall | NYJ @ LV |
| 14 | Kenneth Walker III (GTD) | Sea vs Wsh |
| 15 | Rhamondre Stevenson | NE vs Ind |
| 16 | Rachaad White | TB vs Ten |
| 17 | J.K. Dobbins | Bal vs Cle |
| 18 | Aaron Jones (GTD) | GB @ Pit |
| 19 | Jahmyr Gibbs | Det @ LAC |
| 20 | Cam Akers | Min vs NO |
| Rank | Player | Match |
| 21 | James Conner (GTD) | Ari vs Atl |
| 22 | David Montgomery | Det @ LAC |
| 23 | Javonte Williams | Den @ Buf |
| 24 | Alexander Mattison | Min vs NO |
| 25 | Brian Robinson Jr. | Wsh @ Sea |
| 26 | Najee Harris | Pit vs GB |
| 27 | James Cook | Buf vs Den |
| 28 | Brian Robinson | Wsh @ Sea |
| 29 | Chuba Hubbard | Car @ Chi |
| 30 | Jaylen Warren | Pit vs GB |
| 31 | Zack Moss | Ind @ NE |
| 32 | D'Onta Foreman | Chi vs Car |
| 33 | Jerome Ford | Cle @ Bal |
| 34 | Miles Sanders | Car @ Chi |
| 35 | Gus Edwards | Bal vs Cle |
| 36 | Tyler Allgeier | Atl @ Ari |
| 37 | Jaleel McLaughlin | Den @ Buf |
| 38 | Devin Singletary | Hou @ Cin |
| 39 | A.J. Dillon | GB @ Pit |
| 40 | Ezekiel Elliott | NE vs Ind |
