All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 3:54 PM ET.
| Rank | Player | Match |
| 1 | Austin Ekeler | LAC @ KC |
| 2 | Josh Jacobs | LV @ Chi |
| 3 | Alvin Kamara | NO vs Jax |
| 4 | Raheem Mostert | Mia @ Phi |
| 5 | Christian McCaffrey (GTD) | SF @ Min |
| 6 | Kenneth Walker III | Sea vs Ari |
| 7 | Travis Etienne | Jax @ NO |
| 8 | Saquon Barkley (GTD) | NYG vs Wsh |
| 9 | Bijan Robinson | Atl @ TB |
| 10 | Isiah Pacheco | KC vs LAC |
| 11 | D'Andre Swift | Phi vs Mia |
| 12 | Aaron Jones (GTD) | GB @ Den |
| 13 | Brian Robinson Jr. | Wsh @ NYG |
| 14 | Alexander Mattison | Min vs SF |
| 15 | Jonathan Taylor | Ind vs Cle |
| 16 | Jahmyr Gibbs (GTD) | Det @ Bal |
| 17 | Rhamondre Stevenson (GTD) | NE vs Buf |
| 18 | James Cook | Buf @ NE |
| 19 | Najee Harris | Pit @ LAR |
| 20 | Rachaad White | TB vs Atl |
| Rank | Player | Match |
| 21 | Javonte Williams | Den vs GB |
| 22 | Jerome Ford | Cle @ Ind |
| 23 | Jaylen Warren | Pit @ LAR |
| 24 | Zack Moss | Ind vs Cle |
| 25 | Jaleel McLaughlin | Den vs GB |
| 26 | Kareem Hunt (GTD) | Cle @ Ind |
| 27 | Jordan Mason | SF @ Min |
| 28 | Zach Evans | LAR vs Pit |
| 29 | A.J. Dillon | GB @ Den |
| 30 | Tyler Allgeier | Atl @ TB |
| 31 | Gus Edwards | Bal vs Det |
| 32 | Antonio Gibson | Wsh @ NYG |
| 33 | Ezekiel Elliott | NE vs Buf |
| 34 | D'Onta Foreman | Chi vs LV |
| 35 | Justice Hill | Bal vs Det |
| 36 | Roschon Johnson (GTD) | Chi vs LV |
| 37 | Samaje Perine | Den vs GB |
| 38 | Keaontay Ingram | Ari @ Sea |
| 39 | Eli Mitchell | SF @ Min |
| 40 | David Montgomery (GTD) | Det @ Bal |
