All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 12:19 PM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF vs Ari |
| 2 | Tyreek Hill | Mia @ Buf |
| 3 | Justin Jefferson | Min @ Car |
| 4 | Davante Adams | LV @ LAC |
| 5 | Keenan Allen | LAC vs LV |
| 6 | Tony Pollard | Dal vs NE |
| 7 | Travis Kelce | KC @ NYJ |
| 8 | Ja'Marr Chase | Cin @ Ten |
| 9 | Stefon Diggs | Buf vs Mia |
| 10 | Josh Jacobs | LV @ LAC |
| 11 | Amon-Ra St. Brown | Det @ GB |
| 12 | Derrick Henry | Ten vs Cin |
| 13 | A.J. Brown | Phi vs Wsh |
| 14 | Bijan Robinson | Atl @ Jax |
| 15 | CeeDee Lamb | Dal vs NE |
| 16 | Travis Etienne | Jax vs Atl |
| 17 | Kenneth Walker III | Sea @ NYG |
| 18 | Devon Achane | Mia @ Buf |
| 19 | Deebo Samuel (GTD) | SF vs Ari |
| 20 | Zack Moss | Ind vs LAR |
| 21 | Rhamondre Stevenson | NE @ Dal |
| 22 | Puka Nacua | LAR @ Ind |
| 23 | Jaylen Waddle (GTD) | Mia @ Buf |
| 24 | DeVonta Smith | Phi vs Wsh |
| 25 | Raheem Mostert | Mia @ Buf |
| 26 | Calvin Ridley | Jax vs Atl |
| 27 | Aaron Jones (GTD) | GB vs Det |
| 28 | Miles Sanders (GTD) | Car vs Min |
| 29 | D'Andre Swift | Phi vs Wsh |
| 30 | Kyren Williams | LAR @ Ind |
| 31 | Joe Mixon | Cin @ Ten |
| 32 | Amari Cooper | Cle vs Bal |
| 33 | Tee Higgins | Cin @ Ten |
| 34 | Chris Olave | NO vs TB |
| 35 | Javonte Williams | Den @ Chi |
| Rank | Player | Match |
| 36 | James Conner (GTD) | Ari @ SF |
| 37 | Jakobi Meyers | LV @ LAC |
| 38 | D.K. Metcalf | Sea @ NYG |
| 39 | Jerry Jeudy (GTD) | Den @ Chi |
| 40 | Alvin Kamara | NO vs TB |
| 41 | Michael Pittman Jr. | Ind vs LAR |
| 42 | Alexander Mattison | Min @ Car |
| 43 | Christian Kirk | Jax vs Atl |
| 44 | George Pickens | Pit @ Hou |
| 45 | Marquise Brown | Ari @ SF |
| 46 | Rachaad White | TB @ NO |
| 47 | David Montgomery (GTD) | Det @ GB |
| 48 | Tutu Atwell | LAR @ Ind |
| 49 | Courtland Sutton | Den @ Chi |
| 50 | Brian Robinson | Wsh @ Phi |
| 51 | Mike Evans | TB @ NO |
| 52 | Mark Andrews | Bal @ Cle |
| 53 | Jahmyr Gibbs | Det @ GB |
| 54 | Dameon Pierce | Hou vs Pit |
| 55 | DeAndre Hopkins | Ten vs Cin |
| 56 | T.J. Hockenson | Min @ Car |
| 57 | Jerome Ford (GTD) | Cle vs Bal |
| 58 | James Cook | Buf vs Mia |
| 59 | Tyler Lockett | Sea @ NYG |
| 60 | Austin Ekeler (GTD) | LAC vs LV |
| 61 | Garrett Wilson | NYJ vs KC |
| 62 | Zay Flowers | Bal @ Cle |
| 63 | Tank Dell | Hou vs Pit |
| 64 | Najee Harris | Pit @ Hou |
| 65 | D.J. Moore | Chi vs Den |
| 66 | Jaylen Warren | Pit @ Hou |
| 67 | Nico Collins | Hou vs Pit |
| 68 | Adam Thielen | Car vs Min |
| 69 | Gabriel Davis | Buf vs Mia |
| 70 | George Kittle | SF vs Ari |
