All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 9:20 AM ET.
| Rank | Player | Match |
| 1 | Saquon Barkley | NYG vs Det |
| 2 | Austin Ekeler | LAC vs KC |
| 3 | Christian McCaffrey | SF @ Ari |
| 4 | Joe Mixon | Cin @ Pit |
| 5 | Josh Jacobs | LV @ Den |
| 6 | Jonathan Taylor (GTD) | Ind vs Phi |
| 7 | Dalvin Cook | Min vs Dal |
| 8 | Alvin Kamara | NO vs LAR |
| 9 | Nick Chubb | Cle @ Buf |
| 10 | Rhamondre Stevenson | NE vs NYJ |
| 11 | Dameon Pierce (GTD) | Hou vs Wsh |
| 12 | David Montgomery | Chi @ Atl |
| 13 | James Conner | Ari vs SF |
| 14 | Miles Sanders | Phi @ Ind |
| 15 | Tony Pollard | Dal @ Min |
| 16 | Cordarrelle Patterson | Atl vs Chi |
| 17 | Devin Singletary | Buf vs Cle |
| 18 | Antonio Gibson | Wsh @ Hou |
| 19 | Jamaal Williams | Det @ NYG |
| 20 | Najee Harris | Pit vs Cin |
| Rank | Player | Match |
| 21 | Brian Robinson | Wsh @ Hou |
| 22 | D'Andre Swift | Det @ NYG |
| 23 | Ezekiel Elliott (GTD) | Dal @ Min |
| 24 | D'Onta Foreman | Car @ Bal |
| 25 | Isiah Pacheco | KC @ LAC |
| 26 | Michael Carter | NYJ @ NE |
| 27 | Melvin Gordon | Den vs LV |
| 28 | Jerick McKinnon | KC @ LAC |
| 29 | Kareem Hunt | Cle @ Buf |
| 30 | Darrell Henderson | LAR @ NO |
| 31 | Gus Edwards (GTD) | Bal vs Car |
| 32 | Kenyan Drake | Bal vs Car |
| 33 | Eli Mitchell | SF @ Ari |
| 34 | James Robinson | NYJ @ NE |
| 35 | Latavius Murray | Den vs LV |
| 36 | Jaylen Warren | Pit vs Cin |
| 37 | Tyler Allgeier | Atl vs Chi |
| 38 | Damien Harris (Q) | NE vs NYJ |
| 39 | Chase Edmonds | Den vs LV |
| 40 | Chuba Hubbard | Car @ Bal |
