All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 9:54 AM ET.
| Rank | Player | Match |
| 1 | Jonathan Taylor | Ind vs LV |
| 2 | Alvin Kamara | NO vs Car |
| 3 | Nick Chubb | Cle @ Pit |
| 4 | Dalvin Cook | Min @ GB |
| 5 | David Montgomery | Chi vs NYG |
| 6 | Austin Ekeler | LAC vs Den |
| 7 | Najee Harris | Pit vs Cle |
| 8 | Sony Michel | LAR @ Bal |
| 9 | Aaron Jones | GB vs Min |
| 10 | Joe Mixon | Cin vs KC |
| 11 | Josh Jacobs | LV @ Ind |
| 12 | Ronald Jones | TB @ NYJ |
| 13 | Ezekiel Elliott | Dal vs Ari |
| 14 | D'Andre Swift | Det @ Sea |
| 15 | Devin Singletary | Buf vs Atl |
| 16 | Rashaad Penny | Sea vs Det |
| 17 | Eli Mitchell (GTD) | SF vs Hou |
| 18 | Darrel Williams | KC @ Cin |
| 19 | Saquon Barkley (GTD) | NYG @ Chi |
| 20 | Cordarrelle Patterson | Atl @ Buf |
| Rank | Player | Match |
| 21 | Michael Carter | NYJ vs TB |
| 22 | Damien Harris (GTD) | NE vs Jax |
| 23 | A.J. Dillon | GB vs Min |
| 24 | Javonte Williams | Den @ LAC |
| 25 | Chase Edmonds | Ari @ Dal |
| 26 | Rex Burkhead | Hou @ SF |
| 27 | Melvin Gordon | Den @ LAC |
| 28 | Alexander Mattison | Min @ GB |
| 29 | Jaret Patterson | Wsh vs Phi |
| 30 | Devonta Freeman | Bal vs LAR |
| 31 | Jordan Howard (GTD) | Phi @ Wsh |
| 32 | Tony Pollard | Dal vs Ari |
| 33 | D'Onta Foreman | Ten vs Mia |
| 34 | Rhamondre Stevenson | NE vs Jax |
| 35 | Dare Ogunbowale | Jax @ NE |
| 36 | Duke Johnson | Mia @ Ten |
| 37 | Kareem Hunt (GTD) | Cle @ Pit |
| 38 | Brandon Bolden | NE vs Jax |
| 39 | Chuba Hubbard | Car @ NO |
| 40 | Boston Scott | Phi @ Wsh |
