All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 9:53 AM ET.
| Rank | Player | Match |
| 1 | Dalvin Cook | Min @ Chi |
| 2 | Najee Harris | Pit vs Ten |
| 3 | Leonard Fournette | TB vs NO |
| 4 | Alvin Kamara | NO @ TB |
| 5 | James Robinson | Jax vs Hou |
| 6 | Cordarrelle Patterson | Atl @ SF |
| 7 | Joe Mixon | Cin @ Den |
| 8 | Ezekiel Elliott | Dal @ NYG |
| 9 | David Montgomery | Chi vs Min |
| 10 | Antonio Gibson | Wsh @ Phi |
| 11 | Saquon Barkley | NYG vs Dal |
| 12 | James Conner (GTD) | Ari @ Det |
| 13 | Myles Gaskin | Mia vs NYJ |
| 14 | Aaron Jones | GB @ Bal |
| 15 | Melvin Gordon | Den vs Cin |
| 16 | Darrell Henderson | LAR vs Sea |
| 17 | Devonta Freeman | Bal vs GB |
| 18 | Javonte Williams | Den vs Cin |
| 19 | A.J. Dillon | GB @ Bal |
| 20 | Michael Carter | NYJ @ Mia |
| Rank | Player | Match |
| 21 | Miles Sanders | Phi vs Wsh |
| 22 | Jeff Wilson | SF vs Atl |
| 23 | David Johnson | Hou @ Jax |
| 24 | Chase Edmonds | Ari @ Det |
| 25 | Devin Singletary | Buf vs Car |
| 26 | Tony Pollard (GTD) | Dal @ NYG |
| 27 | Rashaad Penny | Sea @ LAR |
| 28 | Chuba Hubbard | Car @ Buf |
| 29 | D'Onta Foreman | Ten @ Pit |
| 30 | Sony Michel | LAR vs Sea |
| 31 | Craig Reynolds | Det vs Ari |
| 32 | Royce Freeman | Hou @ Jax |
| 33 | Dontrell Hilliard | Ten @ Pit |
| 34 | Mike Davis | Atl @ SF |
| 35 | Godwin Igwebuike | Det vs Ari |
| 36 | Jeremy McNichols | Ten @ Pit |
| 37 | Ameer Abdullah | Car @ Buf |
| 38 | Boston Scott | Phi vs Wsh |
| 39 | JaMycal Hasty | SF vs Atl |
| 40 | Mark Ingram (GTD) | NO @ TB |
