All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 9:31 AM ET.
| Rank | Player | Match |
| 1 | Alvin Kamara | NO @ TB |
| 2 | Chase Edmonds | Ari vs Mia |
| 3 | James Conner | Pit @ Dal |
| 4 | Josh Jacobs (que) | LV @ LAC |
| 5 | Justin Jackson (GTD) | LAC vs LV |
| 6 | Leonard Fournette | TB vs NO |
| 7 | Ronald Jones | TB vs NO |
| 8 | Joshua Kelley | LAC vs LV |
| 9 | Jordan Howard | Mia @ Ari |
| 10 | Ezekiel Elliott (que) | Dal vs Pit |
| 11 | James White | NE @ NYJ |
| 12 | Tony Pollard | Dal vs Pit |
| 13 | La'Mical Perine | NYJ vs NE |
| 14 | Patrick Laird | Mia @ Ari |
| 15 | Damien Harris | NE @ NYJ |
| 16 | Latavius Murray | NO @ TB |
| 17 | Sony Michel (GTD) | NE @ NYJ |
| 18 | Rex Burkhead | NE @ NYJ |
| 19 | Frank Gore | NYJ vs NE |
| 20 | Jalen Richard | LV @ LAC |
| Rank | Player | Match |
| 21 | Devontae Booker | LV @ LAC |
| 22 | Salvon Ahmed | Mia @ Ari |
| 23 | Benny Snell | Pit @ Dal |
| 24 | D.J. Foster | Ari vs Mia |
| 25 | Jonathan Ward | Ari vs Mia |
| 26 | Jaylen Samuels | Pit @ Dal |
| 27 | Ty Johnson | NYJ vs NE |
| 28 | Malcolm Perry | Mia @ Ari |
| 29 | Eno Benjamin | Ari vs Mia |
| 30 | Anthony McFarland Jr. | Pit @ Dal |
| 31 | Rico Dowdle | Dal vs Pit |
| 32 | Ty Montgomery | NO @ TB |
| 33 | Alec Ingold | LV @ LAC |
| 34 | Michael Burton | NO @ TB |
| 35 | Jakob Johnson (GTD) | NE @ NYJ |
| 36 | Ke'Shawn Vaughn | TB vs NO |
| 37 | Troymaine Pope (dou) | LAC vs LV |
| 38 | Chandler Cox | Mia @ Ari |
| 39 | LeSean McCoy (GTD) | TB vs NO |
| 40 | J.J. Taylor | NE @ NYJ |
