All position ranks are: QB RB WR TE FLEX D
These rankings were updated as of Sun 10:35 AM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | Car @ TB |
| 2 | Alvin Kamara | NO @ LV |
| 3 | Ezekiel Elliott | Dal vs Atl |
| 4 | Derrick Henry | Ten vs Jax |
| 5 | Saquon Barkley | NYG @ Chi |
| 6 | Dalvin Cook | Min @ Ind |
| 7 | Kenyan Drake | Ari vs Wsh |
| 8 | Josh Jacobs | LV vs NO |
| 9 | Clyde Edwards-Helaire | KC @ LAC |
| 10 | Aaron Jones | GB vs Det |
| 11 | Austin Ekeler | LAC vs KC |
| 12 | Miles Sanders | Phi vs LAR |
| 13 | Jonathan Taylor | Ind vs Min |
| 14 | David Johnson | Hou vs Bal |
| 15 | James Conner | Pit vs Den |
| 16 | Chris Carson | Sea vs NE |
| 17 | Todd Gurley | Atl @ Dal |
| 18 | Raheem Mostert | SF @ NYJ |
| 19 | Melvin Gordon | Den @ Pit |
| 20 | Ronald Jones | TB vs Car |
| Rank | Player | Match |
| 21 | David Montgomery (GTD) | Chi vs NYG |
| 22 | Devin Singletary | Buf @ Mia |
| 23 | Nyheim Hines | Ind vs Min |
| 24 | Mark Ingram | Bal @ Hou |
| 25 | James Robinson | Jax @ Ten |
| 26 | Malcolm Brown | LAR @ Phi |
| 27 | Zack Moss | Buf @ Mia |
| 28 | Tarik Cohen | Chi vs NYG |
| 29 | James White | NE @ Sea |
| 30 | Antonio Gibson | Wsh @ Ari |
| 31 | D'Andre Swift | Det @ GB |
| 32 | Latavius Murray | NO @ LV |
| 33 | Cam Akers | LAR @ Phi |
| 34 | Sony Michel | NE @ Sea |
| 35 | J.K. Dobbins | Bal @ Hou |
| 36 | Frank Gore | NYJ vs SF |
| 37 | Tevin Coleman | SF @ NYJ |
| 38 | Myles Gaskin (GTD) | Mia vs Buf |
| 39 | Peyton Barber | Wsh @ Ari |
| 40 | Jordan Howard | Mia vs Buf |
