Other Week 6 Ranks: Top 25 QBs || Top 40 RBs || Top 50 WRs
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The Seattle-Oakland game will be played in London.
| Rank | Player | Team | Opp |
| 1 | Travis Kelce | KC | @NE |
| 2 | Rob Gronkowski | NE | KC |
| 3 | George Kittle | SF | @GB |
| 4 | Jared Cook | OAK | SEA |
| 5 | Eric Ebron | IND | @NYJ |
| 6 | Jordan Reed | WSH | CAR |
| 7 | Austin Hooper | ATL | TB |
| 8 | Jimmy Graham | GB | SF |
| 9 | David Njoku | CLE | LAC |
| 10 | Kyle Rudolph | MIN | ARI |
| 11 | Trey Burton | CHI | @MIA |
| 12 | Cameron Brate | TB | @ATL |
| 13 | C.J. Uzomah | CIN | PIT |
| 14 | Greg Olsen | CAR | @WSH |
| 15 | Vance McDonald | PIT | @CIN |
| 16 | Nick Vannett | SEA | OAK |
| 17 | Niles Paul | JAC | @DAL |
| 18 | Geoff Swaim | DAL | JAC |
| 19 | Ricky Seals-Jones | ARI | @MIN |
| 20 | Charles Clay | BUF | @HOU |
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