These standard ranks are updated as of Oct. 12
Other Week 6 Ranks: Top 25 QBs || Top 50 WRs || Top 20 TEs
Build the best lineups with the power of The Machine for Daily Fantasy Sports
The Seattle-Oakland game will be played in London.
| Rank | Player | Team | Opp |
| 1 | Todd Gurley | LAR | @DEN |
| 2 | Melvin Gordon | LAC | @CLE |
| 3 | James Conner | PIT | @CIN |
| 4 | Ezekiel Elliott | DAL | JAX |
| 5 | Kareem Hunt | KC | @NE |
| 6 | Christian McCaffrey | CAR | @WAS |
| 7 | Marshawn Lynch | OAK | SEA |
| 8 | David Johnson | ARI | @MIN |
| 9 | T.J. Yeldon | JAX | @DAL |
| 10 | Sony Michel | NE | KC |
| 11 | Joe Mixon | CIN | PIT |
| 12 | Chris Carson | SEA | @OAK |
| 13 | Carlos Hyde | CLE | LAC |
| 14 | James White | NE | KC |
| 15 | Jordan Howard | CHI | @MIA |
| 16 | Dalvin Cook* | MIN | ARI |
| 17 | Phillip Lindsay | DEN | LAR |
| 18 | Bilal Powell | NYJ | IND |
| 19 | Telvin Coleman | ATL | TB |
| 20 | Alfred Morris | SF | @GB |
Build the best lineups with the power of The Machine for Daily Fantasy Sports.
| Rank | Player | Team | Opp |
| 21 | LeSean McCoy | BUF | @HOU |
| 22 | Chris Thompson | WAS | CAR |
| 23 | Nyheim Hines | IND | @NYJ |
| 24 | Alex Collins | BAL | @TEN |
| 25 | Adrian Peterson | WAS | CAR |
| 26 | Isaiah Crowell | NYJ | IND |
| 27 | Dion Lewis | TEN | BAL |
| 28 | Tarik Cohen | CHI | @MIA |
| 29 | Lamar Miller | HOU | BUF |
| 30 | Javorius Allen | BAL | @TEN |
| 31 | Aaron Jones | GB | SF |
| 32 | Austin Ekeler | LAC | @CLE |
| 33 | Royce Freeman | DEN | LAR |
| 34 | Kenyan Drake | MIA | CHI |
| 35 | Peyton Barber | TB | @ATL |
| 36 | Derrick Henry | TEN | BAL |
| 37 | Mike Davis | SEA | @OAK |
| 38 | Ito Smith | ATL | TB |
| 39 | Ronald Jones | TB | @ATL |
| 40 | Ty Montgomery | GB | SF |
*Assuming the player plays.
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