Also look at these other Week 3 rankings: QB WR TE
These ranks are updated as of Sept. 24 and will be updated throughout the weekend.
Note: The Jaguars-Ravens game will be played in London.
| Rank | Player | Team | Opp |
| 1 | Le'Veon Bell | PIT | @CHI |
| 2 | Jay Ajayi | MIA | @NYJ |
| 3 | Ezekiel Elliott | DAL | @ARI |
| 4 | Devonta Freeman | ATL | @DET |
| 5 | Kareem Hunt | KC | @LAC |
| 6 | Melvin Gordon | LAC | KC |
| 7 | Ty Montgomery | GB | CIN |
| 8 | LeSean McCoy | BUF | DEN |
| 9 | Marshawn Lynch | OAK | @WAS |
| 10 | C.J. Anderson | DEN | @BUF |
| 11 | Dalvin Cook | MIN | TB |
| 12 | Christian McCaffrey | CAR | NO |
| 13 | Mike Gillislee | NE | HOU |
| 14 | Jonathan Stewart | CAR | NO |
| 15 | Lamar Miller | HOU | @NE |
| 16 | Isaiah Crowell | CLE | @IND |
| 17 | Frank Gore | IND | CLE |
| 18 | Jacquizz Rodgers | TB | @MIN |
| 19 | Derrick Henry | TEN | SEA |
| 20 | Chris Carson | SEA | @TEN |
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| Rank | Player | Team | Opp |
| 21 | DeMarco Murray | TEN | SEA |
| 22 | James White | NE | HOU |
| 23 | Samaje Perine | WAS | OAK |
| 24 | Tevin Coleman | ATL | @DET |
| 25 | Tarik Cohen | CHI | PIT |
| 26 | Jordan Howard | CHI | PIT |
| 27 | Ameer Abdullah | DET | @ATL |
| 28 | Chris Thompson | WAS | OAK |
| 29 | Joe Mixon | CIN | @GB |
| 30 | Darren Sproles | PHI | NYG |
| 31 | Mark Ingram | NO | @CAR |
| 32 | Theo Riddick | DET | @ATL |
| 33 | Chris Johnson | ARI | DAL |
| 34 | Duke Johnson | CLE | @IND |
| 35 | Matt Forte | NYJ | MIA |
| 36 | Orleans Darkwa | NYG | @PHI |
| 37 | Giovani Bernard | CIN | @GB |
| 38 | Shane Vereen | NYG | @PHI |
| 39 | Alvin Kamara | NO | @CAR |
| 40 | Bilal Powell | NYJ | @MIA |
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